The total number of mutations (changes) found in the DNA of cancer cells. Knowing the TMB may help plan the best treatment. For example, tumors that have a high number of mutations appear to be more likely to respond to certain types of immunotherapy. TMB is being used as a type of biomarker. Also called tumor mutational burden.
Source: NCI Dictionary of Cancer Terms
Search the Glossary of Medical Terms
Newsletter
Sign up for the QuackTrack.org newsletter below!