monoclonal antibody Ch14.18

A drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and 13-cis-retinoic acid to treat children with high-risk neuroblastoma. It is used in patients whose disease has gotten better with other anticancer treatment. Monoclonal antibody Ch14.18 binds to a substance called GD2, which is found on some types of cancer cells. Monoclonal antibody Ch14.18 may block GD2 and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called Ch14.18, dinutuximab, MOAB Ch14.18, and Unituxin.