epidermal growth factor receptor gene

A gene that makes a protein called epidermal growth factor receptor (EGFR), which is involved in cell growth and cell survival. Mutated (changed) forms of the epidermal growth factor receptor gene and protein have been found in some types of cancer, including non-small cell lung cancer. These changes may cause cancer cells to grow and spread in the body. Checking for changes in the epidermal growth factor receptor gene in tumor tissue may help plan cancer treatment. Also called EGFR gene, ERBB1 gene, and HER1 gene.