A large network of proteins and other molecules that surround, support, and give structure to cells and tissues in the body. The ECM helps cells attach to, and communicate with, nearby cells, and plays an important role in cell growth, cell movement, and other cell functions. The ECM is also involved in repairing damaged tissue. Abnormal changes in the ECM may lead to the development of certain diseases, such as cancer. The ECM of cancer cells can affect how they grow and spread. Also called extracellular matrix.
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