calaspargase pegol

A drug used with other drugs to treat acute lymphoblastic lymphoma in children and young adults aged 1 month to 21 years. Calaspargase pegol is a form of the drug L-asparaginase that is linked to a substance called SC-PEG, which makes the drug stay in the body longer. L-asparaginase is an enzyme taken from the bacterium Escherichia coli (E. coli). It breaks down the amino acid asparagine and may stop the growth of cancer cells that need asparagine to grow. Calaspargase pegol is a type of protein synthesis inhibitor. Also called Asparlas, EZN-2285, and SC-PEG E. coli L-asparaginase.