AZD6244

A drug used to treat a rare genetic condition called neurofibromatosis type 1. It is used in children aged 2 years and older who have plexiform neurofibromas that are causing symptoms and cannot be removed by surgery. It is also being studied in the treatment of some types of cancer. AZD6244 blocks proteins called MEK1 and MEK2, which may help keep abnormal cells or cancer cells from growing and may kill them. It is a type of kinase inhibitor and a type of targeted therapy. Also called Koselugo, MEK inhibitor AZD6244, and selumetinib sulfate.