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Glossary of Medical Terms

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antibacterial

A substance that kills bacteria or stops them from growing and causing disease.

( AN-tee-bak-TEER-ee-ul )

antibiotic

A drug used to treat infections caused by bacteria and other microorganisms.

( AN-tee-by-AH-tik )

antibody

A protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen. An antibody is a type of immunoglobulin.

( AN-tee-BAH-dee )

antibody therapy

Treatment that uses antibodies to help the body fight cancer, infection, or other diseases. Antibodies are proteins made by the immune system that bind to specific markers on cells or tissues. Monoclonal antibodies are a type of antibody made in the laboratory that can be used in diagnosis or treatment. In cancer treatment, monoclonal antibodies may kill cancer cells directly, they may block development of tumor blood vessels, or they may help the immune system kill cancer cells.

( AN-tee-BAH-dee THAYR-uh-pee )

antibody-dependent cell-mediated cytotoxicity

A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of white blood cells. The white blood cells bind to the antibodies and release substances that kill the target cells or microbes. Also called ADCC and antibody-dependent cellular cytotoxicity.

( AN-tee-BAH-dee-deh-PEN-dent sel-MEE-dee-AY-ted SY-toh-tok-SIH-sih-tee )

antibody-dependent cellular cytotoxicity

A type of immune reaction in which a target cell or microbe is coated with antibodies and killed by certain types of white blood cells. The white blood cells bind to the antibodies and release substances that kill the target cells or microbes. Also called ADCC and antibody-dependent cell-mediated cytotoxicity.

( AN-tee-BAH-dee-deh-PEN-dent SEL-yoo-ler SY-toh-tok-SIH-sih-tee )

antibody-drug conjugate

A substance made up of a monoclonal antibody chemically linked to a drug. The monoclonal antibody binds to specific proteins or receptors found on certain types of cells, including cancer cells. The linked drug enters these cells and kills them without harming other cells. Some antibody-drug conjugates are used to treat cancer. Also called ADC.

anticachexia

Describes a drug or effect that works against cachexia (loss of body weight and muscle mass).

( AN-tee-kuh-KEK-see-uh )

anticancer antibiotic

A type of anticancer drug that blocks cell growth by interfering with DNA, the genetic material in cells. Also called antineoplastic antibiotic and antitumor antibiotic.

( AN-tee-KAN-ser AN-tee-by-AH-tik )

anticancer therapy

Treatment to stop or prevent cancer. Types of anticancer therapy include chemotherapy, radiation therapy, surgery, immunotherapy, and others.

( AN-tee-KAN-ser THAYR-uh-pee )

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