COX-2
An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of COX-2 and blocking its activity may reduce tumor growth. Also called cyclooxygenase-2 and prostaglandin-endoperoxide synthase 2.
COX-2 inhibitor
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. COX-2 inhibitors are being studied in the prevention of colon polyps, and as anticancer drugs. Also called cyclooxygenase-2 inhibitor.
Cozaar
A drug used to treat high blood pressure. Cozaar blocks the action of chemicals that make blood vessels constrict (get narrower). It is a type of angiotensin II receptor antagonist. Also called losartan potassium.
CP
A chemotherapy combination used to treat chronic lymphocytic leukemia (CLL). It includes the drugs chlorambucil hydrochloride and prednisone. Also called chlorambucil-prednisone, chlorambucil-prednisone regimen, and CP regimen.
CP regimen
A chemotherapy combination used to treat chronic lymphocytic leukemia (CLL). It includes the drugs chlorambucil hydrochloride and prednisone. Also called chlorambucil-prednisone, chlorambucil-prednisone regimen, and CP.
CP-358,774
A drug used to treat certain types of non-small cell lung cancer. It is also used with gemcitabine hydrochloride to treat pancreatic cancer that cannot be removed by surgery or has spread to other parts of the body. It is being studied in the treatment of other types of cancer. CP-358,774 blocks a protein called epidermal growth factor receptor (EGFR), which may help keep cancer cells from growing. It is a type of EGFR tyrosine kinase inhibitor. Also called erlotinib hydrochloride, OSI-774, and Tarceva.
CP-4055
A drug used to treat advanced acute myeloid leukemia (AML). It is a form of the anticancer drug cytarabine that may work in patients with leukemia that is resistant to cytarabine. CP-4055 blocks cell division and may kill cancer cells. It is a type of antimetabolite. Also called Elacyt and elacytarabine.
CP-547,632
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called vascular endothelial growth factor (VEGF) receptor inhibitors and angiogenesis inhibitors.
CP-609,754
A substance that is being studied in the treatment of cancer.
CP-724,714
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called ErbB receptor tyrosine kinase inhibitors.
